Social media outlets often refer to this disease as "Mold Toxicity". But it is so much more:
Clinical Case Definition: Chronic inflammatory response syndrome (CIRS) is a chronic illness acquired following the exposure to the interior environment of a water-damaged building (WDB) with resident microbes including, but not limited to, filamentous fungi, bacteria, including actinomycetes and mycobacteria; and their toxins and inflammagens, including, but not limited to, hemolysins, beta glucans, mannans, and spirocyclic drimanes. Cases with CIRS-WDB will have multisystem, multi-symptom illness. The presence of multiple reliable objective biomarkers, taken as a group but not individually, will aid in diagnosis and in monitoring therapy. Markers include genetic haplotypes, innate immune inflammatory elements, deficiency in neuroregulatory peptides or their receptors, dysregulation of pituitary and end organ endocrine factors, as well as clearly defined abnormalities in transcriptomics.
Besides the pathogens located in a Water Damaged Building (WDB) there are many other triggers for a CIRS storm: Tick Borne Disease, such as Lyme, Bartonella, Babesia etc., Cyanobacteria and its related toxins often found in algae blooms in ponds, COVID and even the toxins found in a Brown Recluse spider venom.
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